Fig. 1.

Effects of KHG26693 on glutamate-induced cortical neuron injury. Cell viability was determined by MTT assay. (A) Glutamate treatment for 12 h at 37°C decreased cell viability in a concentration-dependent manner (1, 3, 5, 7, and 10 mM). (B) Treatment of KHG26693 at different concentrations (5-50 M) for 12 h at 37°C ameliorated glutamate (5 mM)-induced neuron injury. (C) Time courses of KHG26693 (20 µM) effects on glutamate (5 mM)-induced toxicity. Data are presented as means ± S.D (n = 3). *Indicates statistical significance between glutamate group and glutamate group treated with KHG26693 (P < 0.01) (n = 3).