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. 2020 Aug 21;14(11):2796–2813. doi: 10.1002/1878-0261.12762

Table 2.

Chemoresistance, BRCA status, and homologous recombination (HR) status of HGSOC samples. IC50 values of cisplatin, determined by MTT viability assay. Genetic testing of samples was performed during clinical diagnosis. HR status was confirmed via foci formation assay (see Methods).

Sample Cisplatin (μm) BRCA status HR status
graphic file with name MOL2-14-2796-g006.jpg PDX14 13 WT Deficient
PDX5 4.1 BRCA1 mutation Proficient
PDX9 5.8 WT Proficient
PDX1 25 WT Deficient
PDX3 6.0 WT Proficient
PDX8 1.5 Unknown Deficient
OVCAR8 6.8 WT a Proficient
PDX4 0.7 BRCA2 mutation Deficient
PDX6 0.4 BRCA2 mutation Deficient
a

Methylated [89].