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Validation of the use of optical wave similarity (OWS) for measuring action potential regularity. A) OWS as a function of pacing cycle length (PCL) in optically mapped guinea pig hearts, n = 6. Inset shows example OWS maps at PCL = 170 ms and 90 ms respectively. B) OWS as a function of PCL in optically mapped mouse left atria, n = 7. Inset shows example OWS maps at PCL = 150 ms and 50 ms respectively.
