Table 1.
Demographics, laboratory findings, outcomes of COVID-19 CLC cohort
COVID-19 recoverd N = 19 | COVID-19 deceased N = 6 | P value | |
---|---|---|---|
Median age years(range) | 77 (68-90) | 73 (48-87) | 0.105 |
Men | 18 | 6 | 1.000 |
Caucasian | 19 | 5 | 0.240 |
Cough, # | 7 | 5 | 0.073 |
Dyspnea, # | 1 | 4 | 0.005 |
Median Temp °F (range) | 102 (99.4-104) | 102.3 (97.5-104.6) | 0.338 |
Median SBP mmHg, (range) | 99 (93-112) | 102 (77-154) | 0.246 |
Median Heart Rate bpm, (range) | 81 (81-153) | 102 (65 –122) | 0.036 |
Median Respiratory rate breaths/min | 18 (19-29) | 24 (15-26) | 0.003 |
BMI (range) | 26 (13-29) | 26 (19-41) | 0.591 |
Oxygen saturation on Room Air, % | 92 (84-96) | 86 (70-92) | 0.018 |
Diabetes, # | 6 | 3 | 0.630 |
Hypertension, # | 12 | 4 | 1.000 |
CHF, # | 3 | 1 | 1.000 |
COPD, # | 5 | 2 | 1.000 |
CAD, # | 5 | 3 | 0.344 |
Hemodialysis, # | 1 | 1 | 0.430 |
Number hospitalized | 6 | 3 | 0.630 |
# of influenza tests, viral panels, result | 12 and 3 respectively, NEG | 6 and 3 respectively, NEG | |
Hydroxychloroquine, # | 11 | 3 | 1.000 |
Azithromycin, # | 4 | 2 | 0.606 |
Doxycycline, # | 6 | 3 | 0.600 |
Beta lactam antibiotics, # | 5 | 3 | 0.340 |
Steroids given, # | 0 | 1 | 0.240 |
History of ACEI/ARB use | 4 | 1 | 1.000 |
Median SAPS II score | 32 | 47 | 0.0009 |
Median D-dimer on admission ng/mL | 399 (150-2226) | 1525 (497-3039) | 0.019 |
Median PEAK D-Dimer | 465 (150-2339) | 2592 (887-3039) | 0.0005 |
Median Procalcitonin ng/mL on Admission | 0.1 | 0.25 | 0.042 |
Median PEAK Procalcitonin | 0.1 | 4.56 | 0.023 |
Median CRP mg/L on Admission | 24 | 174 | <0.001 |
Median PEAK CRP | 49 | 188 | 0.003 |
Median Ferritin on Admission ng/mL | 136 (19-1500) | 385 (249-1500) | 0.158 |
Median PEAK Ferritin | 216 (21-1500) | 664 (385-1500) | 0.047 |
Median White Blood Cells/mm3 | 5.3 (3.5-19.6) | 6.4 (4.3–25.1) | 0.230 |
Median Absolute Lymphocytes | 1.2 (0.7-10.6) | 0.7 (0.5–1.0) | 0.312 |
Median Serum Creatinine mg/dL | 1.1 (0.7-6.6) | 1.8 (0.8-6.3) | 0.165 |
Median LDH IU/L | 150 (89-279) | 264 (199-320) | 0.002 |
blood types: | |||
O positive | 2 | 2 | |
O negative | 2 | 0 | |
A positive | 2 | 2 | |
A negative | 2 | 0 | |
B negative | 1 | 0 | |
AB positive | 4 | 1 | |
Unknown | 6 | 1 |
ACEI, ace inhibitor; ARB, angiotensin receptor blocker; BMI, body mass index; CAD, coronary artery disease; CHF, congestive heart failure; COPD, chronic obstructive lung disease; CRP, C-reactive protein; LDH, lactate dehydrogenase; NEG, negative; SAPS II, simplified acute physiologic score II; SBP, systolic blood pressure.