Table 3. . Antiproliferative activities of compound 7 against HeLa and MDA-MB-231 cell lines.
| Compound | IC50 (μM)† | ||
|---|---|---|---|
| HeLa | MDA-MB-231 | MCF-10A | |
| 7a | 6.57 | 5.73 | 5.48 |
| 7c | 5.32 | 5.54 | 6.34 |
| 7e | 5.09 | 7.28 | 7.43 |
| 7f | 5.48 | 5.79 | 6.68 |
| 7h | 10.69 | 11.66 | 12.15 |
| 7j | 2.86 | 4.03 | 2.37 |
| 7k | 8.36 | 9.15 | 7.69 |
| 7m | 6.12 | 7.51 | 6.89 |
| 7n | 5.52 | 4.31 | 5.22 |
| 7o | 6.56 | 7.82 | 9.55 |
| belinostat | 3.23 | 2.35 | 0.41 |
Assays were performed in replicate (n ≥ 2). Mean values are shown, and the standard deviations are <20% of the mean.