Figure 2: Distinct DNA methylation patterns in undifferentiated round cell sarcomas with EWSR1-NFATc2 fusion.
Unsupervised hierarchical clustering (a) and t-Distributed Stochastic Neighbor Embedding (t-SNE) analysis (b) of DNA methylation data from undifferentiated round cell sarcoma variants and a reference set of prototypical soft tissue and bone sarcomas with frequent rearrangements involving gene members of the TET transcription factor family. The arrow points out the novel methylation group.