Table 3.

Retrospective analyses of space–time and spatial variation in temporal trend of Dengue incidence in Brazil Northeast, 2014–2017

a. Space–time
Cluster	Time period	States	Radium (km)	Number of municipalities	Number of cases	Annual rate/100 000	Relative risk	P-value
1	2015–2016	Alagoas, Pernambuco, Paraíba, Rio Grande do Norte and Ceará	533.39	808	287 252	524.3	4.07	< 0.001
2	2015–2016	Bahia (Itabuna)	0.0	1	25 906	5882.8	27.56	< 0.001
3	2016–2017	Maranhão	51.35	2	2153	1049.8	4.69	< 0.001
4	2015–2015	Bahia and Piauí	59.38	4	1012	1092.7	4.87	< 0.001

b. Spatial variation in temporal trend
Cluster	Inside time trend (%)	Localization	Radium (km)	Number of municipalities	Number of cases	Annual rate/100 000	Relative risk	P-value
1	10.53	Rio Grande do Norte and Ceará	155.93	82	101 814	466.3	2.35	0.001
2	84.89	Tocantins and Maranhão	287.79	41	8850	214.6	0.96	0.001
3	19.56	South of Bahia	288.43	65	38 094	434.6	2.01	0.001
4	2354.45	Agreste Pernambucano	11.76	2	662	351.2	1.57	0.001
5	192.11	South of Ceará	18.52	2	920	877.7	3.92	0.001
6	36.93	Ceará and Paraíba	28.82	6	5421	856.7	3.85	0.001
7	23.53	Pernambuco and Alagoas	32.32	14	6109	434.2	1.95	0.001
8	1365.01	West of Bahia	0.0	1	204	392.6	1.75	0.001
9	Inf	Sergipe	0.0	1	2	256.3	0.007	0.001
10	45.23	Zona da mata of Pernambuco	13.59	3	1626	319.6	1.43	0.001
11	3.14	East of Pernambuco and Paraíba	52.02	25	21 042	346.3	1.57	0.001
12	89.79	Agreste Pernambucano	0.0	1	358	181.4	0.81	0.001
13	2.87	East of Pernambuco	45.90	15	13 000	204.4	0.91	0.001
14	28.12	Sertão of Paraíba	12.32	3	1106	725.3	3.24	0.001
15	128.66	Sergipe	0.0	1	85	71.5	0.32	0.001
16	52.06	Paraíba	0.0	1	238	136.15	0.61	0.001
17	42.88	Pernambuco	11.19	3	273	119.9	0.53	0.001
18	17.80	Bahia	0.0	1	783	294.6	1.31	0.001
19	5.02	Pernambuco	18.94	5	2842	155.2	0.69	0.001
20	40.71	Bahia	40.75	2	242	67.9	0.30	0.001
21	28.15	Alagoas	0.0	1	385	383.7	1.71	0.001
22	4.28	Paraíba and Pernambuco	29.07	5	2543	1502.5	7.77	0.001
23	43.77	Pernambuco	0.0	1	157	157.7	0.70	0.001
24	Inf	Piauí	0.0	1	11	56.1	0.25	0.001
25	45.81	Alagoas	0.0	1	123	452.5	2.02	0.001
26	15.03	Piauí	117.04	30	488	40.2	0.18	0.001
27	19.66	Paraíba	0.0	1	327	248.4	1.11	0.001
28	25.48	Alagoas and Sergipe	25.48	4	722	213.0	0.95	0.001

Inf Infinite