Table 5.
Organ doses in μGy/MBq for several 18F-based imaging agents are compared. RGD-K5, FDG, HX4 data are using 4.8 hr bladder voiding model, Galacto-RGD using 2.0 hr bladder voiding model, and FMISO data using 4.0 hr bladder voiding model.
| RGD-K5 | FDG | Galacto-RGD | FMISO | HX-4 | |
|---|---|---|---|---|---|
| Adrenals | 10 | 13 | 5.4 | 16.6 | 9.6 |
| Brain | 4.8 | 19 | 1.5 | 8.6 | 5 |
| Breasts | 5.2 | 9.2 | 2.0 | 12.3 | 6 |
| Gallbladder Wall | 104 | 14 | 7.6 | 14.8 | 24 |
| Heart Wall | 7.5 | 60 | 3.5 | 18.5 | 9 |
| Kidneys | 45 | 20 | 29.5 | 15.7 | 20 |
| Liver | 26 | 16 | 23 | 18.3 | 14 |
| Lower Large Intestine Wall | 27 | 17 | 12 | 14.3 | 28 |
| Lungs | 6.6 | 17 | 6.6 | 9.9 | 8 |
| Muscle | 9 | 11 | 5.3 | 14.2 | 10 |
| Osteogenic Cells | 10.3 | 12 | 3.8 | 7.7 | 12 |
| Ovaries | 19 | 17 | 11.1 | 17.6 | 18 |
| Pancreas | 10 | 26 | 5.4 | 17.9 | 10 |
| Red Marrow | 8.2 | 13 | 3.9 | 10.9 | 9 |
| Skin | 5.7 | 8.4 | 2.3 | 4.8 | 7 |
| Small Intestine | 20 | 14 | 15.4 | 13.2 | 17 |
| Spleen | 8.2 | 37 | 16.3 | 16.3 | 9 |
| Stomach Wall | 8.6 | 13 | 4.1 | 12.6 | 9 |
| Testes | 13 | 13 | 4.4 | 14.6 | 13 |
| Thymus | 6.2 | 12 | 2.5 | 15.5 | 8 |
| Thyroid | 5.9 | 10 | 2.09 | 15.1 | 8 |
| Upper Large Intestine Wall | 25 | 13 | 16 | 14 | 18 |
| Urinary Bladder Wall | 376 | 190 | 218 | 29 | 299 |
| Uterus | 31 | 23 | 17.4 | 18.3 | 28 |