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. 2020 Nov 2;25:47. doi: 10.1186/s11658-020-00238-5

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Function of STAT3 in hepatocellular carcinoma. a STAT3 in hepatocellular carcinoma was evaluated by IHC. b STAT3 in hepatocellular carcinoma tissue was explored by qRT-PCR. c STAT3 in hepatocellular carcinoma cell lines. d Transfection efficiency of si-STAT3 in Huh7 cells. e, f STAT3 inhibition reduced Huh7 cell proliferation and invasion abilities. g, h High STAT3 levels were correlated with poor prognosis in hepatocellular carcinoma patients. *p < 0.05