Table 1.
Laboratory values for all three patients.
| Case 1 | Case 2 | Case 3 | |
|---|---|---|---|
| WBC (k/mm3) | 18.9 | 23.5 | 17.0 |
| Neutrophils (%), lymphocytes (%), monocytes (%), eosinophils (%), basophils (%) | 96, 2, 1, 0, 0 | 93, 6, 1, 0, 0 | 95.8, 3, 1, 0, 0.2 |
| Hemoglobin (g/dL)/hematocrit (%) | 12.0/35.2 | 12.8/37 | 12.6/37.7 |
| Platelets (k/mm3) | 344 | 412 | 334 |
| Alanine transferase, ALT (U/L) | 11 | 13 | 34 |
| Aspartate transferase, AST (U/L) | 22 | 23 | 35 |
| Total bilirubin (mg/dL) | 0.6 | 1 | < 0.3 |
| CRP (mg/dL) | 29.4 | 33.5 | 35.4 |
| Procalcitonin (ng/mL) | 3.17 | Not done | 0.81 |
| Blood gas (pH/pCO2/pO2/HCO3−) | 7.45/36/75/25 | 7.39/33/79/20 | 7.43/36/108/24 |
| Respiratory viral panela | Negative | Negative | Negative |
| Blood culture | Negative | Negative | Negative |
| SARS-CoV-2 RNAb | Not tested | Negative | Negative |
| BAL cell count (total count, % polys, % lymphocytes, % histiocytes, % macrophages) | 700, 50, 4, 12, 34 | Not done | 798, 86, 1, 10, 3 |
| BAL lipid laden macrophages (Oil red O stain) | <1% | Not done | 15%–20% |
| BAL cultures (bacterial, fungal, and mycobacterial) | Negative | Not done | Negative |
| Legionella cultures (BAL) | Negative | Not done | Negative |
| Streptococcal antigen (Urine) | Not done | Not done | Negative |
BAL: bronchoalveolar lavage; CRP: C-reactive protein; WBC: white blood cell.
a
Respiratory viral panel includes influenza A, influenza B, respiratory syncytial virus (RSV), parainfluenza, coronavirus (not including SARS-CoV-2), human metapneumovirus, rhinovirus/enterovirus, adenovirus, Chlamydia pneumoniae, Mycoplasma pneumoniae.
b
Internally developed Roche Diagnostics Cobas 6800 System that has 91% sensitivity and 100% specificity.