Figure 6.
Effect of miR-147a on H1299 cell tumor growth and metastasis in vivo: (a) NSCLC H1299 cells were transfected with miR-147a and then implanted into nude mice. Tumor volume was measured each week, (b) Tumors were removed and embedded in paraffin for immunohistochemical staining with CCL5 and (c) Metastatic lesions in the lungs of the H1299 metastasis model are shown at 2 weeks after injection of transfected cells into the tail vein. **P < 0.01, compared with control. NSCLC, non-small-cell lung cancer; CCL5, CC chemokine ligand 5. Values are shown as mean ± SD.