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. 2020 Nov 2;21:755. doi: 10.1186/s12864-020-07131-7

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 9 — Model showing predicted pathway(s) for genes that co-cluster with the ERK MAPK genes in Cluster 40. The MAK-1 and MAK-2 ERK MAPK cascade genes are represented by green and red shading, respectively. S. cerevisiae interaction data for genes in Cluster 40 were obtained from www.yeastgenome.org. Physical interactions, genetic interactions, or physical and genetic interactions between the indicated genes/gene products in yeast are shown by yellow, blue, or green lines, respectively. Genes with known interactions in N. crassa are connected by black lines. Genes that interact with the MAK-1 cascade kinases are shaded in yellow, while those that interact with components of the MAK-2 pathway are indicated with blue shading. Genes with no ortholog in yeast and no known interaction in N. crassa are represented by the white rectangles