Table 3.
Univariate and multivariable logistic regression analysis for eventual treatment with EBRT.
| Risk factors for EBRT | Univariate logistic regression analysis | Multivariable logistic regression analysis | ||||
|---|---|---|---|---|---|---|
| Crude OR | 95% CI | p value | Adjusted OR | 95% CI | p value | |
| Age (Each 1 year increase) | 1.010 | 1.000–1.019 | 0.052 | 1.021 | 1.009–1.032 | <0.001 |
| Tumour group by ICRB (A) | 0.029 | – | – | 0.029 | ||
| B | 2.432 | 0.530–11.148 | 0.253 | 2.752 | 0.499–15.165 | 0.245 |
| C | 4.725 | 0.907–24.603 | 0.065 | 9.023 | 1.401–58.101 | 0.021 |
| D | 2.660 | 0.573–12.349 | 0.212 | 6.709 | 1.138–39.562 | 0.036 |
| E | 0.933 | 0.185–4.719 | 0.934 | 3.676 | 0.537–25.180 | 0.185 |
| Presence of subretinal seeds | 0.585 | 0.333–1.025 | 0.061 | – | – | – |
| Plaque radiotherapy | 2.754 | 0.993–7.637 | 0.052 | 3.331 | 1.067–10.396 | 0.038 |
| Absence of enucleation | 0.504 | 0.284–0.893 | 0.019 | 0.427 | 0.198–0.921 | 0.030 |
| Number of TTT applications (=0) | 0.014 | 0.014 | ||||
| 1–4 | 2.133 | 1.194–3.809 | 0.011 | 2.149 | 1.095–4.218 | 0.026 |
| 5–9 | 2.689 | 1.043–6.932 | 0.041 | 4.188 | 1.394–12.580 | 0.011 |
EBRT external beam radiotherapy, OR odds ratio, CI confidence interval, ICRB international classification of retinoblastoma, TTT transpupillary thermotherapy.