Skip to main content
. 2020 Mar 31;41(10):1366–1376. doi: 10.1038/s41401-020-0389-3

Table 3.

Effects of the selective inhibitors on the formation of metabolites during HLMs incubations

Name MS area Relative MS area (%)
HLM ANF QUE SPZ TCL QD KET CMT ABT
Control 1A2 2C8 2C9 2B6/2C19 2D6 3A 2E1 CYPS
M0 2.47 × 105 89 92 58 61 94 227 87 165
M224 2.32 × 103 127 70 88 94 80 36 100 26
M484 2.42 × 103 101 62 89 84 39 136
M486 5.77 × 103 147 31 92 86 113 18 131 19
M497 1.49 × 103 81 37 62 62 40 89
M539 1.82 × 103 67 57 62 55 58 81
M554-1 2.12 × 103 96 53 58 58 100 109 83 76
AST5902 7.84 × 104 97 32 55 62 54 14 88 2
M555 2.24 × 103 74 51 65 44 64 0 73
M584-1 1.04 × 103 112 38 65 143 121 59 115
M584-2 1.83 × 103 126 76 85 77 161 96 31
M584-3 1.74 × 103 80 82 99 75 66 32 122 32
M586 9.00 × 102 117 64 91 111 88 111
M600 2.60 × 103 95 85 85 104 93 13 102 12