Table 2.
Ocular co-pathology and known risk factors for the ISBCS and DSCS operations.
| N (Column %) | ISBCS eyes (N = 2146) | DSCS eyes (N = 496,682) | OR | 95% CI for OR | p value | % of DSCS eyes at their: | |
|---|---|---|---|---|---|---|---|
| First eye surgery | Second eye surgery | ||||||
| No ocular co-pathology or know risk factors | 1134 (52.8) | 306,356 (61.7) | 1.436 | 1.282–1.610 | <0.001 | 59.4 | 64.0 | 
| At least one ocular co-pathology or known risk factor | 1012 (47.2) | 190,326 (38.3) | 40.6 | 36.0 | |||
| The presence of | |||||||
| Age-related macular degeneration | 147 (6.9) | 47,123 (9.5) | 0.702 | 0.558–0.882 | 0.002 | 9.6 | 9.3 | 
| Amblyopiaa | 34 (1.6) | 7835 (1.6) | 1.004 | 0.690–1.462 | 0.982 | 1.7 | 1.4 | 
| Brunescent/white/mature cataracta | 319 (14.9) | 16,385 (3.3) | 5.118 | 4.367–5.999 | <0.001 | 4.2 | 2.4 | 
| Corneal pathology | 62 (2.9) | 14,142 (2.8) | 1.015 | 0.725–1.421 | 0.930 | 3.0 | 2.7 | 
| Diabetic retinopathya | 113 (5.3) | 25,299 (5.1) | 1.036 | 0.799–1.342 | 0.791 | 5.1 | 5.1 | 
| Glaucoma | 152 (7.1) | 39,346 (7.9) | 0.886 | 0.706–1.113 | 0.298 | 8.1 | 7.7 | 
| High myopiaa | 139 (6.5) | 24,034 (4.8) | 1.362 | 1.074–1.727 | 0.011 | 5.3 | 4.4 | 
| Inherited eye diseases | 31 (1.4) | 662 (0.1) | 10.982 | 6.616–18.229 | <0.001 | 0.1 | 0.1 | 
| No fundal view/vitreous opacitiesa | 142 (6.6) | 4164 (0.8) | 8.381 | 6.647–10.568 | <0.001 | 1.3 | 0.4 | 
| Other macular pathology | 25 (1.2) | 8522 (1.7) | 0.675 | 0.424–1.076 | 0.099 | 1.8 | 1.7 | 
| Other retinal vascular pathology | 13 (0.6) | 3416 (0.7) | 0.880 | 0.440–1.761 | 0.718 | 0.7 | 0.7 | 
| Optic nerve/CNS disease | 24 (1.1) | 1705 (0.3) | 3.283 | 1.900–5.675 | <0.001 | 0.4 | 0.3 | 
| Pseudoexfoliation/Phacodenesisa | 21 (1.0)) | 4100 (0.8) | 1.187 | 0.671–2.102 | 0.556 | 0.9 | 0.8 | 
| Previous retinal detachment | 9 (0.4) | 2079 (0.4) | 1.002 | 0.486–2.067 | 0.996 | 0.6 | 0.2 | 
| Previous vitrectomy | 20 (0.9) | 3538 (0.7) | 1.311 | 0.764–2.249 | 0.325 | 1.0 | 0.4 | 
| Previous trabeculectomya | 3 (0.1) | 1439 (0.3) | 0.482 | 0.155–1.497 | 0.207 | 0.3 | 0.3 | 
| Uveitis/Synaechiae | 13 (0.6) | 2923 (0.6) | 1.029 | 0.483–2.196 | 0.940 | 0.7 | 0.5 | 
| Unspecified ‘other’ ocular co-pathologya | 148 (6.9) | 26,896 (5.4) | 1.294 | 1.034–1.619 | 0.024 | 6.0 | 4.9 | 
CI = confidence interval
aThese conditions are included in the case complexity adjustment for PCR