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. 2020 Jun 12;28(10):1387–1393. doi: 10.1038/s41431-020-0651-7
Breast
No Recommendations Grading
1 Women should be screened for breast cancer Strong
2 Surveillance for breast cancer in PHTS should use MRI (MRI should be ideally conducted between day 5 and day 12 of the menstrual cycle) Strong
3 Surveillance for breast cancer with MRI should probably start at 30 Strong
4 Women should be screened for breast cancer annually Strong
5. If surveillance for breast cancer in PHTS additionally includes mammography this should be undertaken no more frequently than every 2 years Moderate
6 If surveillance for breast cancer with mammography is offered this should probably start at 40 Moderate
7 Risk reduction surgery should be offered using the same considerations as for women with germline BRCA1/BRCA2 pathogenic variants Moderate