Cancer Surveillance Guideline for individuals with PTEN hamartoma tumour syndrome

. 2020 Jun 12;28(10):1387–1393. doi: 10.1038/s41431-020-0651-7

Endometrial
No	Recommendations	Grading
1	Women should probably not be screened for endometrial cancer.	Moderate
2^a	If surveillance for endometrial cancer is offered it should be as part of a clinical trial.	Strong
3^a	If surveillance for endometrial cancer is offered, it should probably start at 40.	Weak
4^a	If surveillance for endometrial cancer is offered, it should probably be done at least annually.	Weak
5	There is no clinical indication for endometrial cancer risk reduction surgery (hysterectomy).	Weak

^aNB: Recommendations 2–5, should be undertaken as part of a clinical trial.