Table 2.
Development of the visual field, visual acuity, Swinging-flash-light-Test (SWFLT), Arden color test including protan and tritan values.
| Visit 1 | Visit 2 | Visit 3 (post) | Visit 4 | |||||
|---|---|---|---|---|---|---|---|---|
| Surgery | Steroid-Pulse only | Surgery | Steroid-Pulse only | Surgery | Steroid-Pulse only | Surgery | Steroid-Pulse only | |
| Visual field | ||||||||
| Defects | ||||||||
| Yes | 26 | 11 | 23 | 13 | 10 | 6 | 2 | 4 |
| No | 1 | – | – | 1 | 3 | 4 | 12 | 4 |
| Missing | 3 | 5 | 7 | 2 | 17 | 6 | 16 | 6 |
| MDa | −7.2 (−14.9 to −3.5) | −10.2 (−15.9 to −5.3) | −8.6 (−14 to −4.3) | −7.0 (−11.3 to −4.6) | −5.7 (−20.8 to −3.8) | −4.1 (−11.0 to −2.5) | −2.3 (−3.2 to −0.4) | −3.1 (-5.8 to −0.5) |
| Visual acuity | ||||||||
| Visusa | 0.26 (0.13–0.50) | 0.57 (0.40–0.80) | 0.20 (0.07–0.27) | 0.63 (0.43–0.80) | 0.32 (0.10–0.50) | 0.63 (0.43–0.80) | 0.50 (0.32–0.80) | 0.90 (0.67–1.00) |
| Logmara | 0.6 (0.3–1.0) | 0.3 (0.1–0.4) | 0.7 (0.6 –11.5) | 0.2 (0.1–0.4) | 0.5 (0.3–1.0) | 0.2 (0.1–0.4) | 0.3 (0.1–0.5) | 0.1 (0–0.2) |
| SWFLT | ||||||||
| Negative | 23 | 14 | 21 | 14 | 27 | 16 | 28 | 16 |
| Positive | 7 | 2 | 9 | 2 | 3 | – | 2 | – |
| Color test | ||||||||
| Abnormal | 19 | 11 | 13 | 3 | 25 | 8 | 7 | 4 |
| Normal | 5 | 4 | 4 | 3 | 1 | 3 | 9 | 2 |
| Missing | 6 | 1 | 13 | 10 | 4 | 10 | 14 | 10 |
| Protana | 37.00 (6.23–100.00) | 9.90 (5.20–18.40) | 38.56 (10.45–97.15) | 8.00 (5.30–18.40) | 15.40 (6.00–94.90) | 5.80 (3.53–14.98) | 6.70 (3.53–12.85) | 8.40 (6.73–17.93) |
| Tritana | 45.7 (18.58–100) | 26.30 (13.70–35.80) | 60.85 (19.78–100) | 26.90 (10.90–40.60) | 62.80 (17.65–100) | 15.65 (12.00–20.83) | 13.70 (8.40–42.60) | 17.35 (11.10–30.63) |
Visit 1: Diagnosis of dysthyroid optic neuropathy (DON) and begin the treatment with steroid-pulse therapy.
Visit 2: The visit after the medical decompression (in three patients, this visit took place during the steroid-pulse treatment owing to worsening of symptoms).
Visit 3: for the medical decompression only group: the second follow-up visit after the steroid-pulse treatment. For the surgical decompression group: first follow-up visit after the surgery.
Visit 4: last visit of the patients.
aMedian, 25–75th percentile shown.