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. 2019 Dec 9;34(9):1631–1639. doi: 10.1038/s41433-019-0691-9

Table 2.

Ocular exposures associated with household cleaning products by product subcategory and medical outcome, National Poison Data System 2000–2016

Product subcategories/generic product namesb Exposures followed to known medical outcomes
Totala No effect Minor effect Moderate effect Major effect
n (col. %)c n (row %)d n (row %)d n (row %)d n (row %)d
Bleaches 82,599 (25.9) 2222 (4.3) 43,651 (84.2) 5893 (11.4) 64 (0.1)
  Hypochlorite (liquid and dry) 80,153 (25.1) 2127 (2.7) 42,390 (52.9) 5720 (7.1) 58 (0.1)
Miscellaneous Cleaners 48,146 (15.1) 2186 (6.9) 25,436 (80.0) 4100 (12.9) 87 (0.3)
   Miscellaneous cleaning agents: alkalis 13,278 (4.2) 568 (4.3) 7049 (53.1) 1593 (12.0) 43 (0.3)
  Miscellaneous cleaning agents: anionics or nonionics 8689 (2.7) 361 (4.2) 4690 (54.0) 592 (6.8) 17 (0.2)
  Miscellaneous cleaning agents: cationics 6152 (1.9) 195 (3.2) 3034 (49.3) 771 (12.5) 15 (0.2)
  Miscellaneous cleaning agents: isopropanol (excluding automotive products and glass) 5831 (1.8) 323 (5.5) 3051 (52.3) 156 (2.7) 1 (0.0)
  Miscellaneous cleaning agents: other or unknown household cleaning agents 7987 (2.5) 434 (5.4) 4245 (53.1) 579 (7.2) 10 (0.1)
Wall/floor/tile cleaners 42,841 (13.4) 2343 (8.1) 23,498 (81.3) 2990 (10.3) 64 (0.2)
  Wall/floor/tile/all-purpose Cleaning agents: acids 7717 (2.4) 437 (5.7) 4609 (59.7) 517 (6.7) 13 (0.2)
  Wall/floor/tile/all-purpose cleaning agents: alkalis 17,953 (5.6) 961 (5.4) 9651 (53.8) 1404 (7.8) 33 (0.2)
  Wall/floor/tile/all-purpose cleaning agents: anionics or nonionics 6616 (2.1) 329 (5.0) 3530 (53.4) 546 (8.3) 5 (0.1)
  Wall/floor/tile/all-purpose cleaning agents: cationics 4680 (1.5) 236 (5.0) 2427 (51.9) 218 (4.7) 4 (0.1)
Disinfectants 34,591 (10.8) 1,508 (6.9) 18,174 (82.7) 2263 (10.3) 41 (0.2)
  Disinfectants: hypochlorite (non-bleach products) 13,820 (4.3) 395 (2.9) 6749 (48.8) 1207 (8.7) 20 (0.1)
  Disinfectants: other or unknown 14,273 (4.5) 781 (5.5) 7895 (55.3) 697 (4.9) 10 (0.1)
  Disinfectants: phenol 3110 (1.0) 170 (5.5) 1763 (56.7) 145 (4.7) 7 (0.2)
  Disinfectants: pine oil 3388 (1.1) 162 (4.8) 1767 (52.2) 214 (6.3) 4 (0.1)
Laundry detergents 19,338 (6.1) 440 (3.4) 10,398 (80.8) 1983 (15.4) 41 (0.3)
  Laundry detergents: granules (various containers) 6258 (2.0) 173 (2.8) 3493 (55.8) 401 (6.4) 7 (0.1)
  Laundry detergents: liquids (unit dose) 5020 (1.6) 94 (1.9) 2745 (54.7) 778 (15.5) 20 (0.4)
  Laundry detergents: liquids (various containers) 7502 (2.3) 156 (2.1) 3854 (51.4) 737 (9.8) 13 (0.2)
Glass cleaners 16,825 (5.3) 1497 (13.7) 8961 (82.1) 452 (4.1) 4 (0.0)
  Glass cleaners: ammonia containing 8833 (2.8) 880 (10.0) 4737 (53.6) 181 (2.0) 2 (0.0)
   Glass cleaners: isopropanol 4894 (1.5) 363 (7.4) 2587 (52.9) 144 (2.9) 2 (0.0)
Toilet bowl cleaners 14,911 (4.7) 517 (4.7) 8937 (81.8) 1450 (13.3) 19 (0.2)
  Toilet bowl cleaners: acids 8845 (2.8) 287 (3.2) 5665 (64.0) 932 (10.5) 10 (0.1)
  Toilet bowl cleaners: alkalis 4082 (1.3) 148 (3.6) 2223 (54.5) 363 (8.9) 6 (0.1)
Laundry prewash/stain removers 13,324 (4.2) 681 (7.3) 7481 (80.5) 1103 (11.9) 23 (0.2)
  Laundry prewash/stain removers: liquid surfactant based 4458 (1.4) 204 (4.6) 2406 (54.0) 491 (11.0) 10 (0.2)
  Laundry prewash/stain removers: other or unknown 5665 (1.8) 303 (5.3) 3273 (57.8) 301 (5.3) 7 (0.1)
Miscellaneous cleaning substances (household) 9050 (2.8) 574 (9.7) 4879 (82.2) 468 (7.9) 11 (0.2)
  Carpet, upholstery, leather, or vinyl cleaners 6326 (2.0) 8 (0.0) 3478 (1.1) 304 (0.1) 416 (0.1)
Hand dishwashing 7312 (2.3) 176 (3.8) 4013 (85.6) 491 (10.5) 7 (0.1)
  Anionic or nonionic hand dishwashing detergents 5511 (1.7) 135 (2.4) 3091 (56.1) 369 (6.7) 7 (0.1)
Oven cleaners 5968 (1.9) 183 (4.4) 2691 (65.1) 1210 (29.3) 47 (1.1)
  Oven cleaners: alkalis 5203 (1.6) 161 (3.1) 2358 (45.3) 1083 (20.8) 41 (0.8)
Cleansers 5712 (1.8) 287 (7.8) 2942 (79.5) 466 (12.6) 7 (0.2)
 Other types/unknown household cleaners 3532 (1.1) 177 (5.0) 1762 (49.9) 330 (9.3) 6 (0.2)
Drain cleaners 5401 (1.7) 158 (4.3) 2474 (68.0) 957 (26.3) 50 (1.4)
  Drain cleaners-alkalis 4009 (1.3) 104 (2.6) 1807 (45.1) 736 (18.4) 43 (1.1)
Automatic dishwasher detergents 5201 (1.6) 140 (4.1) 2782 (80.8) 505 (14.7) 14 (0.4)
Spot removers/dry cleaning agents 2820 (0.9) 149 (8.1) 1538 (83.2) 160 (8.7) 2 (0.1)
Laundry additives 2412 (0.8) 145 (9.1) 1324 (82.6) 128 (8.0) 5 (0.3)
Rust removers 1855 (0.6) 61 (4.5) 1033 (76.0) 261 (19.2) 4 (0.3)
Fabric softeners/antistatic agents 1202 (0.4) 76 (9.7) 656 (83.7) 52 (6.6) 0 (0.0)
Total 319,508 (100.0) 13,343 (6.4) 170,868 (81.5) 24,932 (11.9) 490 (0.2)

aTotal includes exposures with medical outcomes of “not followed (minimal clinical effects possible)” and “unable to follow, judged as a potentially toxic exposure”

bSelected generic products were included if they accounted for ≥1% of all exposures

cColumn percentages were calculated using the total number of exposures as the denominator

dRow percentages for each product were calculated using only the total number of exposures followed to a known medical outcome