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. 2019 Nov 19;34(9):1577–1584. doi: 10.1038/s41433-019-0694-6

Table 1.

Clinical and imaging features of patients with optic disc drusen: visible vs. buried

Visible ODD Buried ODD p value
(n = 8) (n = 30)
Age, years (mean ± SD) 14 ± 4 11 ± 4 0.11
Female:male ratio, female % 4:4 (50%) 23:7 (77%) 0.14
BCVA (LogMAR) (mean ± SD) 0.00 ± 0.00 0.03 ± 0.05 0.11
Spherical equivalent (D) (mean ± SD) −1.41 ± 0.69 −0.46 ± 1.81 0.16
Mean scleral canal diameter ratio V:H (µm) 1788:1675 1561:1436 <0.01
Visual field defects, n (%) 2 (25%) 5 (17%) 0.04
ODD related complications, n (%) 1 (13%) 2 (7%) 0.60
ODD EDI-OCT, n (%) 8 (100%) 30 (100%)
PHOMS EDI-OCT, n (%) 6 (75%) 28 (93%) 0.13
Fundus auto-fluorescence, n (%) 4 (50%) 15 (50%) 0.65
Ophthalmic ultrasound, n (%) 8 (100%) 24 (80%) 0.17
RNFL thickness, µm (mean ± SD) 104 ± 27 107 ± 26 0.80

BCVA best-corrected visual acuity, D dioptres, EDI-OCT enhanced depth imaging optical coherence tomography, PHOMS peripapillary hyperreflective ovoid mass-lie structures, RNFL retinal nerve fibre layer, ODD optic disc drusen, SD standard deviation, V:H vertical:horizontal