Table 3.
Association between the presence of ODD and PHOMS with RNFL thickness decrease evaluated by ONH sector
| Sector | RNFL lossa, n (%) | Normal RNFL, n (%) | ODD, n | Chi2 (df) | p value |
|---|---|---|---|---|---|
| ODD | |||||
| Nasal | 7 (30%) | 16 (70%) | 23 | 5.60 (1) | 0.02* |
| Superonasal | 4 (27%) | 11 (73%) | 15 | 3.96 (1) | 0.05* |
| Superotemporal | 4 (44%) | 5 (56%) | 9 | 2.81 (1) | 0.09 |
| Temporal | 1 (11%) | 8 (89%) | 9 | 0.81 (1) | 0.37 |
| Inferotemporal | 7 (50%) | 7 (50%) | 14 | 4.78 (1) | 0.03* |
| Inferonasal | 4 (19%) | 17 (81%) | 21 | 1.43 (1) | 0.23 |
| Sector | RNFL lossa, n (%) | Normal RNFL, n (%) | PHOMS, n | Chi2 (df) | p value |
|---|---|---|---|---|---|
| PHOMS | |||||
| Nasal | 3 (20%) | 12 (80%) | 15 | 0.04 (1) | 0.84 |
| Superonasal | 3 (19%) | 13 (81%) | 16 | 0.76 (1) | 0.38 |
| Superotemporal | 2 (17%) | 10 (83%) | 12 | 0.48 (1) | 0.49 |
| Temporal | 1 (10%) | 9 (90%) | 10 | 0.61 (1) | 0.44 |
| Inferotemporal | 5 (42%) | 7 (58%) | 12 | 2.13 (1) | 0.14 |
| Inferonasal | 2 (15%) | 11 (85%) | 13 | 0.90 (1) | 0.77 |
Chi2 chi-square test for independence, df degrees of freedom, EDI-OCT enhanced depth imaging optical coherence tomography, PHOMS peripapillary hyperreflective ovoid mass-lie structures, RNFL retinal nerve fibre layer, ODD optic disc drusen
*Statistically significant difference (p ≤ 0.05)
aPatients categorised with a RNFL loss presented values that were outside or borderline below normal limits