Table 3.
Significant correlations of metabolites and RS connectivity between IBS and HC females.
| Metabolites | RS connectivity | r | p valuea |
|---|---|---|---|
| Histidine | Left PosDCgG to Left Pu | 0.21 | 0.016 |
| Cysteine | Left PosDCgG to Left Pu | 0.19 | 0.030 |
| Glycine | Left PosDCgG to Left Pu | 0.17 | 0.043 |
| Glutamate | Left PosDCgG to Left Pu | 0.18 | 0.042 |
| Spermidine | Left PosDCgG to Left Pu | 0.17 | 0.050 |
| Anserine | Left PosDCgG to Left Pu | 0.18 | 0.040 |
| Histidine | Right SupFG to Right Pu | 0.20 | 0.022 |
| Tryptophan | Right SupFG to Right Pu | 0.17 | 0.050 |
| Uracil | Right SupFG to Right Pu | 0.22 | 0.010 |
| 2-Deoxyuridine | Right SupFG to Right Pu | 0.19 | 0.027 |
| Thymidine | Right SupFG to Right Pu | 0.20 | 0.022 |
| Succinate | Right SupFG to Right Pu | −0.19 | 0.029 |
PosDCgG dorsal part of the posterior cingulate gyrus, SupFG superior frontal gyrus, Pu putamen.
aPartial correlation analysis between metabolites and RS connectivity controlling for age, BMI, and diet was performed.