Table 3.
Univariate and multivariate Cox analysis for PINK1 and PARK2 protein expression (overall survival as endpoint).
| Parameter | Univariate Cox analysis | Multivariate Cox analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | p-value | HR | 95%CI | p-value | |
| PINK1 | ||||||
| High | 1.0 | – | – | 1.0 | – | – |
| Low | 3.1 | 1.2–8.0 | 0.016 | 3.61 | 1.2–11.0 | 0.024 |
| PARK2 | ||||||
| High | 1.0 | – | – | |||
| Low | 1.6 | 0.7–3.7 | 0.263 | |||
| pT-stage | ||||||
| pT1 | 1.0 | – | – | 1.0 | – | – |
| pT2 or pT3 | 2.80 | 1.3–6.0 | 0.008 | 2.3 | 1.0–5.5 | 0.059 |
| pN-status | ||||||
| pN0/cN0 | 1.0 | – | – | 1.0 | – | – |
| pN1 | 5.2 | 1.9–14.0 | 0.001 | 2.7 | 0.8–8.6 | 0.09 |
| M-status | ||||||
| M0 | 1.0 | – | – | |||
| M1 | 7.34 | 3.05–17.62 | 9.7e−06 | |||