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. 2020 Nov 2;11:5531. doi: 10.1038/s41467-020-19371-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — a The RNA secondary structure for each RNA from top to bottom: human telomerase P2ab, fluoride riboswitch, preQ1 Class I riboswitch and preQ1 Class II riboswitch. The bps at different helices used for defining the Euler angles are highlighted in yellow. b The NMR structure bundles. c The FARFAR-NMR ensembles with ensemble size (N) labeled below. Different structural elements are color-coded according to a. The average bend angles < |β_h|> (N = 10 × 200 = 2000) of the two helices are labeled along with the ensembles. d Comparison of the FARFAR-NMR conformer (cyan) with the closest heavy-atom RMSD to the NMR structure (red).