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. 2020 Nov 3;15(11):e0241536. doi: 10.1371/journal.pone.0241536

Table 5. Pooled estimates of secondary attack rates, only high and moderate quality studies.

First Author Number of Index Patients Type of Contacts Traced in Study Contacts Secondary Attack Rate
Number of Contacts Tested Number of Contacts Testing Positive (95% CI)
Park, S. 4° Household Contacts Only 11 0 0%
(0% to 28.5%)
Park, S. 4°° Household Contacts Only 4 0 0%
(0% to 60.2%)
Ye, F. 1° Close Contacts 44 4 9.1%
(2.5% to 21.7%)
Huang, L. 1° Close Contacts 22 7 31.8%
(13.9% to 54.9%)
Li, P. 1° Household Contacts Only 5 4 80%
(28.4% to 99.5%)
Xiao, W. 2° Household and Close Contacts 10 3 30%
(6.7% to 65.2%)
Simple Pooled Estimate 13 96 18 18.8%*

Abbreviations: 95% CI, 95% confidence interval.

*Estimates have been simply pooled to facilitate interpretation of the body of evidence. Since studies are too heterogeneous in methods of contact tracing, confidence intervals on these estimates have not been calculated to not overstate any sense of precision.

°Index patients were pre-symptomatic (exposure occurred prior to symptom onset).

°°Index patients remained asymptomatic.

†Confidence intervals calculated for individual studies only, using the Clopper-Pearson exact method.