Figure 4.

Cell type–specific expression of eGFR and UACR genes in the human single-cell dataset. Heat map showing expression of genes implicated in eGFR (upper) and UACR (lower) across cell types (x axis) in the human single-cell dataset. The expression values are z-score transformed. Genes known to underlie primary monogenic kidney diseases are colored in blue. AVR, ascending vasa recta; DCT, distal convoluted tubule; DVR, descending vasa recta; Fib, fibroblast; GE, glomerular epithelium; IC-A, intercalated cell type A; IC-B, intercalated cell type B; LOH, loop of Henle; MC, mesangial cell; NE, nephron epithelium; Podo, podocyte.