Table 2.
Rates and unadjusted and adjusted odds of hospital mortality and of a DNR order on admission to the ICU per major organ disease, compared with patients with no organ disease
| Characteristic | No Major Organ Disease | Stroke | Cancer | CHF | Dementia | COPD | Cirrhosis | ESKD |
|---|---|---|---|---|---|---|---|---|
| N | 64,093 | 8099 | 14,222 | 13,498 | 3338 | 13,935 | 1517 | 3022 |
| Hospital mortality | ||||||||
| n (%) | 3929 (6.1) | 861 (10.6) | 1649 (11.6) | 1592 (11.8) | 487 (14.6) | 1,558 (11.1) | 250 (16.4) | 394 (13.0) |
| Unadjusted | Reference | 1.23 1.15 to 1.33 | 1.58 1.49 to 1.67 | 1.46 1.37 to 1.54 | 1.87 1.69 to 2.06 | 1.35 1.28 to 1.44 | 2.33 2.02 to 2.67 | 1.60 (1.43 to 1.78) |
| Adjusted | Reference | 1.05 0.97 to 1.14 | 1.35 1.27 to 1.43 | 1.16 1.09 to 1.23 | 1.11 1.01 to 1.23 | 1.18 1.11 to 1.26 | 2.67 2.30 to 3.08 | 1.47 1.31 to 1.65 |
| DNR order on admission to the ICU | ||||||||
| n (%) | 1957 (3.1) | 815 (10.1) | 1202 (8.5) | 1365 (10.1) | 827 (24.8) | 1205 (8.7) | 77 (5.1) | 166 (5.5) |
| Unadjusted | Reference | 1.64 1.51 to 1.79 | 1.76 1.65 to 1.89 | 1.96 1.83 to 2.09 | 5.85 5.36 to 6.37 | 1.51 1.40 to 1.61 | 1.03 0.81 to 1.30 | 0.89 0.76 to 1.05 |
| Adjusted | Reference | 1.32 1.21 to 1.43 | 1.29 1.21 to 1.39 | 1.29 1.20 to 1.38 | 2.19 2.00 to 2.40 | 1.19 1.10 to 1.28 | 1.38 1.07 to 1.75 | 1.16 0.98 to 1.37 |
Data are displayed as odds ratio with 95% CI. Adjusted for age, sex, race/ethnicity, admission diagnosis, and the other major organ diseases. Reference category is critically ill patients without organ disease.