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. 2020 Aug 27;31(10):2393–2399. doi: 10.1681/ASN.2020010088

Table 3.

Rates and unadjusted and adjusted odds of hospital mortality and of a DNR order on admission to the ICU in patients with single or multiple organ diseases, compared with those with no organ disease

Characteristic No Major Organ Disease Stroke only Cancer only CHF only Dementia only COPD only Cirrhosis only ESKD only More Than One Organ Disease
N 64,093 4074 9294 6442 1529 6863 983 1445 12,150
Hospital mortality
n (%) 3929 (6.1) 340 (8.3) 970 (10.4) 641 (10.0) 200 (13.1) 643 (9.4) 149 (15.1) 162 (11.2) 1640 (13.5)
 Unadjusted Reference 1.40 1.24 to 1.56 1.78 1.65 to 1.92 1.69 1.55 to 1.85 2.32 2.00 to 2.71 1.58 1.45 to 1.72 2.75 2.29 to 3.27 1.93 1.63 to 2.27 2.39 2.29 to 3.26
 Adjusted Reference 1.03 0.91 to 1.16 1.45 1.33 to 1.56 1.20 1.09 to 1.31 1.17 0.99 to 1.36 1.24 1.13 to 1.36 2.98 2.47 to 3.59 1.60 1.33 to 1.89 1.58 1.47 to 1.68
DNR order on admission to the ICU
n (%) 1957 (3.1) 304 (7.5) 614 (6.6) 511 (7.9) 353 (23.1) 421 (6.1) 32 (3.3) 41 (2.8) 1477 (12.2)
 Unadjusted Reference 2.50 2.26 to 2.90 2.24 2.04 to 2.46 2.73 2.47 to 3.02 9.53 8.38 to 10.8 2.07 1.86 to 2.31 1.07 0.73 to 1.49 0.92 0.67 to 1.25 4.39 4.09 to 4.71
 Adjusted Reference 1.54 1.34 to 1.76 1.46 1.32 to 1.61 1.44 1.29 to 1.61 2.52 2.20 to 2.89 1.28 1.13 to 1.43 1.41 1.32 to 1.61 1.02 0.73 to 1.39 1.99 1.84 to 2.15

Data are displayed as odds ratio with 95% CI. Adjusted for age, sex, race/ethnicity, admission diagnosis, and the other major organ diseases. Reference category is critically ill patients without organ disease.