| XIST |
- Localizes to the entire inactive X chromosomes and recruits machineries for imparting repressive chromatin marks. |
[79] |
| KCNQ1OT1 |
- Involved in bidirectional silencing of genes in the Kcnq1 domain. |
[80] |
|
- Interacts with the H3K9- and H3K27-specific histone methyltransferases G9a and the PRC2 complex, respectively in a lineage-specific manner in the placenta. |
| AIR |
- Controls the Igf2r imprinting cluster in mouse by recruiting the G9a histone methyltransferase to silence target genes. |
[81] |
| HOTAIR |
- Transcribes from the HOXC locus on human Chr12 and represses transcription in trans across 40 kilobases of the HOXD locus on Chr2. |
[66,82] |
|
- Binds to the histone methyltransferase PRC2 complex and the histone demethylase LSD1/CoREST/REST complex at its 5′ domain 3′ ends, respectively. |
| MALAT1 |
- Localizes to nuclear speckles and interacts with pre-mRNA splicing factors and active chromatin |
[69] |
| NEAT1 |
- Forms paraspeckles by interacting with RNA binding proteins. |
[14,69] |
| SAT III |
- Upon stress transcribes from pericentric repeats and forms nuclear stress bodies. |
[83] |
|
- Recruits RNA processing factors to nuclear stress bodies. |
| COLDAIR |
- Represses a floral repressor FLOWERING LOCUS C (FLC) by interacting with PRC2 during vernalization in Arabidopsis thaliana. |
[84] |
| roX1 and roX2 |
- Recruit the dosage-compensation complex on the male X chromosome in a cell-type-specific fashion in Drosophila. |
[85,86] |
