Table 1. Mφ MT1-MMP inactivation does not affect homeostatic cardiac function.
Echocardiography and electrocardiography comparisons between 10-week-old WT and MAC-Mmp14 KO mice. Data are means ± SEM of 10 mice per group. Unpaired t-test. BW, body weight; FS, fraction shortening; HR, heart rate; HW, heart weight; LVEF, LV ejection fraction; LVIDd, LV end-diastolic internal diameter; LVIDs, LV end-systolic internal diameter; LVVold, LV end-diastolic volume; LVVols, LV end-systolic volume.
| WT | MAC-Mmp14 KO | |
|---|---|---|
| BW (g) | 18.62 ± 2.00 | 19.53 ± 2.25 |
| HW/BW (mg/g) | 4.91 ± 0.28 | 4.94 ± 0.19 |
| HR (beats/min) | 462 ± 14 | 463 ± 17 |
| PR (ms) | 39.82 ± 1.18 | 37.70 ± 1.21 |
| QRS (ms) | 25.41 ± 1.06 | 26.18 ± 0.88 |
| LVEF (%) | 53.52 ± 1.72 | 53.14 ± 2.31 |
| LVVols (µL) | 21.53 ± 1.36 | 19.98 ± 1.60 |
| LVVold (µL) | 25.26 ± 0.96 | 22.22 ± 0.90 |
| FS (%) | 26.58 ± 0.89 | 26.33 ± 1.51 |
| LVIDs (mm) | 3.67 ± 0.06 | 3.54 ± 0.08 |
| LVIDd (mm) | 2.7 ± 0.06 | 2.62 ± 0.10 |