Table 3.
Effect ILs-induced NK cells and NK cells number toward breast cancer cells growth inhibition
| Comparison breast cancer (MCF7) and NK cell | ||||
|---|---|---|---|---|
| ILs-induced NK cells (ILs-NK) | (1:5) | (1:2) | (1:1) | (2:1) |
| Control | ||||
| (non-induced NK) | 85.01±2.65 aD | 65.16±4.21 aC | 42.19±5.60 aB | 16.79±1.08 aA |
| IL2-NK (5 ng/ml) | 101.42±1.26 aD | 78.22±1.91 aC | 65.02±2.23 aB | 35.71±0.72 bcA |
| IL2-NK ( 10 ng/ml) | 98.79±4.20 aD | 77.74±9.39 aC | 58.72±1.86 aB | 37.64±1.70 cA |
| IL15-NK (5 ng/ml) | 86.75±10.58 aC | 66.22±4.10 aB | 44.68±7.10 aA | 34.65±4.75 bcA |
| IL15-NK (10 ng/ml) | 86.83±13.86 aC | 69.64±8.53 aBC | 47.03±11.93 aAB | 37.83±8.25 cA |
| IL18-NK (5 ng/ml) | 87.58±1.98 aB | 77.78±4.79 aB | 47.66±17.77 aA | 25.28±3.28 abA |
| IL18-NK (10 ng/ml) | 86.01±1.52 aD | 67.62±6.79 aC | 52.45±1.08 aB | 30.04±1.75 bcA |
* This research was performed 3 replication. The data of cells inhibition (%) are presented as mean ±standard deviation, different small letters in the same column (among concentrations of ILs (IL-2, IL-15, IL-18) treatment on comparison MCF7 and NK cell (1:5, 1:2, 1:1, 2:1), different capital letters in the same row (among ratio MCF7 and NK cells) in each ILs concentrations.