Table 1.
Clinical characteristics of patients with T2DM by BMI category.
| Normal weight group (20–24.9 kg/m2) |
Overweight/obese group (≥25 kg/m2) |
P value | |
|---|---|---|---|
| n | 29 | 50 | |
| Sex (F, %) | 25 (51.7%) | 20 (40%) | 0.312 |
| Age (years) | 59.0 ± 8.6 | 53.6 ± 10.4 | 0.019 |
| DM course (years) | |||
| 0-1 | 7 (24.1%) | 13 (26.0%) | |
| 1-10 | 14 (48.3%) | 21 (42.0%) | 0.858 |
| >10 | 8 (27.6%) | 16 (32.0%) | |
| History of DM | 10 (34.5%) | 16 (32.0%) | 0.821 |
| Hypertension | 11 (37.9%) | 25 (50.0%) | 0.299 |
| Gastrointestinal disorders | 4 (13.8%) | 6 (12.0%) | 1.000 |
| Smoking | 7 (24.1%) | 19 (38.0%) | 0.206 |
| Drinking | 6 (20.7%) | 19 (38.0%) | 0.111 |
| HbA1c (%) | 9.6 (4.2) | 9.0 (2.4) | 0.376 |
| TC (mmol/L) | 4.84 ± 1.17 | 4.55 ± 1.04 | 0.268 |
| TG (mmol/L) | 1.41 (1.01) | 1.59 (1.18) | 0.095 |
| HDL-C (mmol/L) | 1.13 ± 0.21 | 1.02 ± 0.21 | 0.031 |
| LDL-C (mmol/L) | 3.18 ± 0.74 | 3.00 ± 0.75 | 0.303 |
| VLDL-C (mmol/L) | 0.46 (0.22) | 0.47 (0.38) | 0.508 |
| ApoA1 (mmol/L) | 1.32 ± 0.21 | 1.27 ± 0.19 | 0.294 |
| ApoB (mmol/L) | 0.82 ± 0.25 | 0.81 ± 0.19 | 0.831 |
| Total protein (g/L) | 68.53 ± 6.46 | 68.06 ± 5.90 | 0.743 |
| Albumin (g/L) | 40.95 ± 2.86 | 41.41 ± 2.29 | 0.749 |
| BUN (mmol/L) | 4.91 ± 1.27 | 5.14 ± 1.30 | 0.442 |
| Cr (μmmol/L) | 66.35 ± 12.02 | 70.44 ± 13.07 | 0.180 |
| 25OHD (ng/mL) | 13.18 (9.81) | 15.25 (9.92) | 0.248 |
| OC (ng/mL) | 15.05 ± 4.09 | 14.18 ± 5.26 | 0.421 |
| β-CTX (ng/mL) | 0.40 (0.29) | 0.38 (0.33) | 0.827 |
| P1NP (ng/mL) | 38.77 (17.46) | 42.76 (29.99) | 0.935 |
| PTH (pg/mL) | 41.55 ± 14.00 | 41.19 ± 14.89 | 0.915 |
| OP | 20 (69.0%) | 15 (30.0%) | 0.001 |
Note: data were expressed as number (%) or mean ± SD/median (interquartile range). Abbreviations: ApoA1: apolipoprotein A1; ApoB: apolipoprotein B; BMD: bone mineral density; BMI: body mass index; BUN: blood urea nitrogen; Cr: creatinine; DM: diabetes mellitus; HbA1c: glycated hemoglobin; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; T2DM: type 2 diabetes mellitus; TC: total cholesterol; TG: triglyceride; VLDL-C: very-low-density lipoprotein cholesterol; OC: osteocalcin; OP: osteoporosis; P1NP: procollagen type 1 N-terminal propeptide; PTH: parathyroid hormone; 25OHD: 25-hydroxyvitamin D; β-CTX: β-C-terminal cross-linked telopeptide of type I collagen.