Table 1. Mtb strategies for escaping phagolysosomal fusion.

Effectors/factors		Strategy	Ref.
Mtb effectors
	ESAT-6-CFP-10	Inhibition of phagolysosomal fusion	(31)
	Rv3671c	Maintenance of intrabacterial pH	(32)
	TDM	Inhibition of phagosomal acidification and promotion of virulence	(33)
	PtpA	Interaction with V-ATPase and inhibition the recruitment of V-ATPase to phagosome	(39)
	SapM & PknG	Blockade of Mtb delivery to autophagolysosomes	(42)
Host factors
	CISH	Degradation of V-ATPase catalytic subunit A	(43)
	WASH	Accumulation of V-ATPase of phagosomal vacuole to escape phagosomal acidification	(44)
	IL-27	Neutralization of lysosomal acidification and cathepsin D activity	(45)