Table 3.
Comparison of clinical and laboratory parameters between survivors and non-survivors.
| Survivors (n = 78) | Non-Survivors (n = 30) | P-value | |
|---|---|---|---|
| Age | 48.8 ± 17 | 57.5 ± 18.1 | 0.02 |
| Sex (M/F) | 51/27 (65.4%/34.6%) | 19/11 (63.3%/36.7%) | 0.84 |
| Duration of symptoms (in days) | 3.9 ± 2.1 | 4.3 ± 3.1 | 0.41 |
| Presence of co-morbidities | 31 (39.7%) | 19 (63.3%) | 0.03 |
| Hypertension | 24 (30.7%) | 17 (56.7%) | 0.01 |
| Diabetes | 21 (26.9%) | 14 (46.7%) | 0.05 |
| Cardiovascular disease | 9 (11.5%) | 5 (16.7%) | 0.47 |
| Heart Rate (per min) | 86.3 ± 11.6 | 98.8 ± 18.5 | <0.0001 |
| Systolic blood pressure (mm Hg) | 124.6 ± 17.8 | 105.6 ± 21.2 | <0.0001 |
| Haemoglobin (gm/dL) | 12.8 ± 2.3 | 12.2 ± 2.6 | 0.18 |
| Total leucocyte count (per mm3) | 7948.3 ± 3968.4 | 10924.7 ± 7387.6 | 0.008 |
| Absolute lymphocytic count (per mm3) | 1650.4 ± 771.1 | 1059.5 ± 642.2 | 0.0001 |
| Lymphopenia | 17 (21.8%) | 18 (60%) | <0.0001 |
| NLR | 4.75 ± 4.66 | 11.81 ± 10.37 | <0.0001 |
| Platelet count (105/mL) | 2.19 ± 0.79 | 1.77 ± 0.96 | 0.02 |
| Admission blood sugar (mg/dl) | 120.3 ± 55.8 | 184.5 ± 125.8 | <0.0001 |
| ESR (mm/hr) | 41.0 ± 29.1 | 58.9 ± 30.6 | 0.024 |
| Aspartate aminotransferase (U/L) | 32.2 ± 17.2 | 182.1 ± 428.6 | 0.002 |
| Alanine aminotransferase (U/L) | 30.9 ± 21 | 108.9 ± 303.2 | 0.025 |
| Blood Urea (mg/dl) | 33.2 ± 26.8 | 61.1 ± 46.8 | <0.0001 |
| Serum Creatinine (mg/dl) | 1.4 ± 1.7 | 1.7 ± 1.5 | 0.36 |
| CK-MB (U/L) | 23.4 ± 14.3 | 38.8 ± 29.4 | 0.01 |
| Troponin T (μg/L) | 0.10 ± 0.49 | 0.61 ± 1.31 | 0.02 |
| D-dimer positivitya | 26/65 (40%) | 12/14 (85.7.%) | 0.01 |
| Serum LDH (U/L) | 638.1 ± 261.6 | 1530.2 ± 1455.4 | <0.0001 |
| SOFA score | 1.65 ± 2.04 | 5.83 ± 2.53 | <0.0001 |
| Acute cardiac injury | 12 (15.4%) | 16 (53.3%) | <0.0001 |
CK-MB: creatine kinase myocardial band; CRP: C-reactive protein; ECG: electrocardiogram; ESR: erythrocyte sedimentation rate; F: female; gm/dl: gram per deciliter; LDH: Lactate dehydrogenase; M: male; μg/L: microgram per litre; mg/dl: milligram per deciliter; mL: milliliter; mm per hr: millimeter per hour; NLR: neutrophil to lymphocyte ratio; SOFA: sequential organ function assessment; U/L: units per liter.
A P-value ≤0.05 was considered as statistically significant (highlighted in bold).
Done in 79 patients.