Figure 1. Mixed-curvature constructs accumulate along the interior edge of endosomes.
TEM images of macrophages after treatment with (a) mixed-curvature and (b) constant-curvature CpG-constructs. Images in boxes indicate zoomed-in views. The two types of CpG-constructs were incubated at the same concentration of CpG (200 nM). The representative TEM images were collected from three independent treatments.