Table 1.
Associations between NPI variables and cognitive diagnosis
| Nondemented N (%) |
PDD N (%) |
OR | 95% CI | p value | |
|---|---|---|---|---|---|
| Delusions | 14 (2.4) | 18 (16.7) | 7.3 | 3.0 – 17.7 | <0.001† |
| Hallucinations | 43 (7.3) | 40 (37.4) | 7.5 | 4.0 – 14.1 | <0.001† |
| Agitation | 75 (12.8) | 30 (27.8) | 1.9 | 1.1 - 3.5 | 0.029 |
| Depression | 203 (34.6) | 52 (48.2) | 1.5 | 0.9 – 2.4 | 0.142 |
| Anxiety | 94 (16.0) | 33 (30.6) | 2.9 | 1.7 – 5.0 | <0.001† |
| Elation | 11 (1.9) | 5 (4.6) | 3.1 | 0.9 – 10.3 | 0.069 |
| Apathy | 103 (17.6) | 48 (44.4) | 2.2 | 1.3 – 3.6 | 0.004† |
| Disinhibition | 46 (7.9) | 20 (18.5) | 2.8 | 1.4 – 5.5 | 0.002† |
| Irritability | 104 (17.8) | 32 (29.6) | 1.9 | 1.1 – 3.4 | 0.022 |
| Aberrant Motor Behavior | 39 (6.7) | 17 (15.7) | 1.8 | 0.9 – 3.8 | 0.108 |
†
Significant after correcting for multiple comparisons (p<0.005)
Abbreviations: CI, confidence interval; NPI, Neuropsychiatric Inventory; OR, odds ratio; PDD, Parkinson’s disease dementia