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. 2020 Nov 3;10:18923. doi: 10.1038/s41598-020-75014-8

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Calculation of the tree of genealogy of neurodegenerative diseases (NDs). Spy of the adjacency matrix A before sorting for: (a) male and (b) female. Blue squares mark the steps in general. The green squares denote promoters of common steps. The promoters of common steps are marked only in the first disease where the step is found to be common but not in the remaining diseases with this common step. Promoter is the first common step found. Red squares mark the non-common steps. The red-bordered yellow squares mark the spy of the matrices used to position each ND on the tree of the genealogy of NDs. Number of steps and deflections calculated for each ND for: (c) male and (d) female.