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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2020 Jul 25;26(11):2147–2154. doi: 10.1016/j.bbmt.2020.07.024

Table 3.

Correlation between CAST detection and past anti-CMV immunity in recipients before alloHCT and donors

A. All recipients
Pre-alloHCT
CASTs
Anti-CMV IgG serology before alloHCT p-value
Negative
(N=169)
N (%)
Positive
(N=146)
N (%)
< 1 cell / μL 167 (99) 66 (45) <0.0001
≥ 1 cell / μL 2 (1) 80 (55)
B. HLA matched sibling donors
Pre-alloHCT
CASTs
Anti-CMV IgG serology p-value
Negative
(N=25)
N (%)
Positive
(N=26)
N (%)
< 1 cell / μL 25 (100) 6 (23) <0.0001
≥ 1 cell / μL 0 20 (77)

Abbreviations: alloHCT – allogeneic hematopoietic cell transplant, CAST – CMV antigen specific T cell, CMV – cytomegalovirus, HLA – human leukocyte antigen, IgG – immunoglobulin G, N – number