. Author manuscript; available in PMC: 2021 Nov 1.

Published in final edited form as: Biol Blood Marrow Transplant. 2020 Jul 25;26(11):2147–2154. doi: 10.1016/j.bbmt.2020.07.024

Table 5.

Effect of CMV reactivation on CASTs

A. CMV reactivation before day+100 correlates with increased CASTs reconstitution at day+100 in R+D+, R+D-, and R-D+ pairs. Second parenthesis denote horizontal percentages.
Day+100 CAST level	CMV reactivation before day+100						p-value
Day+100 CAST level	No (N=65) N (%)			Yes (N=54) N (%)			p-value
<3/uL (N=57)	42 (66) (75)			14 (26) (25)			<0.0001
≥3/uL (N=62)	22 (34) (35)			40 (74) (65)			<0.0001
B. A range of CMV antigenemia before day+100 is associated with increased CASTs at day+100 in R+D+, R+D-, and R-D+ pairs.
Change in CASTs from before alloHCT to day+100	CMV antigenemia (PMNs+pp65) upon CMV reactivation before day+100						p-value
Change in CASTs from before alloHCT to day+100	None	1-2	3-5	6-9	10-24	≥25	p-value
Same or lower	43 (70)	9 (15)	3 (5)	2 (3)	1 (2)	3 (5)	0.03
Higher	21 (37)	18 (32)	7 (12)	5 (9)	2 (4)	4 (7)	0.03

Abbreviations: alloHCT – allogeneic hematopoietic cell transplant, CAST – CMV antigen specific T cell, CMV – cytomegalovirus, D – donor CMV serotype, N – number, PMNs+pp65 – polymorphonuclear cells positive for pp65 antigen, R-recipient CMV serotype.