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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Neurobiol Aging. 2020 Jul 14;95:81–93. doi: 10.1016/j.neurobiolaging.2020.07.005

Figure 2. Flowchart of MTL sub-structure GWAS design.

Figure 2.

Abbreviations: ASHS, automatic segmentation of hippocampal subfields; SNPs, single nucleotide polymorphisms; MTL, medial temporal lobe; HC, healthy control; EMCI, early mild cognitive impairment; LMCI, late mild cognitive impairment; AD, Alzheimer’s disease; CA, cornu ammonis; DG, dentate gyrus; SUB, subiculum; ERC, entorhinal cortex; PHC, parahippocampal cortex; BA, Brodmann area; VBM, voxel-based morphometry; FDG-PET, Fludeoxyglucose - positron emission tomography; IGAP, International Genomics of Alzheimer’s Project; ADNI, Alzheimer’s Disease Neuroimaging Initiative; UKBEC, UK Brain Expression Consortium; AHBA, Allen human brain atlas; ROI, region of interest; ERC1: ELKS/RAB6-interacting/CAST family member 1.