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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Neurobiol Aging. 2020 Jul 14;95:81–93. doi: 10.1016/j.neurobiolaging.2020.07.005

Figure 5. Association of ERC1 rs2968869 with VBM gray matter density and FDG metabolism in the right hippocampal region.

Figure 5.

(A) Mean right hippocampal gray matter density with standard errors is plotted against the rs2968869 genotype groups (i.e., TT, CT and CC). P value indicates the significance of the association between rs2968869 and mean right hippocampal gray matter density, with age, gender, education and the top four principal components from population stratification analysis as covariates. The C allele of rs2968869 is associated with increased right hippocampal gray matter density. (B) Mean right hippocampal FDG-PET glucose metabolism with standard errors is plotted against the rs2968869 genotype groups (i.e., i.e., TT, CT and CC). The C allele of rs2968869 is associated with increased FDG-PET measured glucose metabolism in right hippocampus.