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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Ophthalmol Retina. 2020 May 7;4(11):1069–1082. doi: 10.1016/j.oret.2020.04.029

Table 3.

Association of Averaged and Single Quantitative Metrics with BCVA

Variable Association with BCVA (Univariate Linear Regression) (Averaged Images) Association with BCVA (Univariate Linear Regression) (Single Images)
Coefficient P Coefficient P
FAZ size 0.211 0.004* −0.095 0.313
FAZ circularity −0.223 0.016* −0.214 0.015*
SRL superior VLD −0.012 0.004* −0.015 0.001*
SRL inferior VLD −0.011 0.055 −0.014 0.008*
SRL nasal VLD −0.016 0.019* −0.015 0.003*
SRL temporal VLD −0.017 0.001* −0.017 0.002*
SRL inner ring VLD −0.020 <0.001* −0.019 <0.001*
SRL total VLD −0.024 <0.001* −0.022 <0.001*
DRL superior VLD −0.017 <0.001* −0.018 0.001*
DRL inferior VLD −0.012 0.046* −0.014 0.038*
DRL nasal VLD −0.016 0.005* −0.016 0.012*
DRL temporal VLD −0.013 0.009* −0.012 0.058
DRL inner ring VLD −0.020 <0.001* −0.021 0.006*
DRL total VLD −0.025 <0.001* −0.025 0.004*
SRL superior PD −0.577 0.046* −0.943 0.003*
SRL inferior PD −0.200 0.617 −0.928 0.026*
SRL nasal PD −0.443 0.366 −0.966 0.020*
SRL temporal PD −0.798 0.074 −1.032 0.010*
SRL inner ring PD −1.862 0.007* −1.624 0.001*
SRL total PD −2.594 <0.001* −1.907 <0.001*
DRL superior PD −0.752 0.004* −0.941 0.002*
DRL inferior PD −0.266 0.616 −0.767 0.094
DRL nasal PD −0.656 0.041* −0.765 0.018*
DRL temporal PD −0.653 0.018* −0.673 0.037*
DRL inner ring PD −1.488 0.001* −1.345 0.003*
DRL total PD −2.190 0.001* −1.759 0.003*

Results of univariate linear regressions for the ability of listed variables to predict BCVA (logMAR) in patients with DR. (+) coefficient = worse logMAR BCVA versus (−) coefficient = better logMAR BCVA. Bold (*) values denote significance set at P < 0.05. PD, perfusion density, is defined as the total area covered by perfused vasculature per unit area (%); VLD, vessel length density, is defined as the total length of perfused vasculature per unit area (mm/mm2). BCVA = best corrected visual acuity (in logarithm of the minimum angle of resolution). DRL = deep retinal layer. FAZ = foveal avascular zone. SD = standard deviation. SRL = superficial retinal layer.