Fig. 6.

The effects of GW3965 on endogenous glutamate and GABA in mouse amygdala. Mouse amygdala from each group were collected and subjected to high-performance liquid chromatography (HPLC) analysis. (a) Representative elution time of glutamate and GABA by HPLC assay. The concentrations of (b) glutamate and (c) GABA in the amygdala were determined immediately after last stimuli with or without GW3965 (GW, 10 mg/kg, i.p.) administration. The concentrations of (d) glutamate and (e) GABA in amygdala were determined 24 h after last stimuli with or without GW (10 mg/kg, i.p.) treatment. Error bars represented SEM. n = 4, *p < 0.05, **p < 0.01, versus control group; ^#p < 0.05, ^##p < 0.01, versus FS2 group