Table 2.
The area under the curve (AUC), sensitivity and specificity values of DE-miRNAs.
| miRNA | AUC | 95% CI | P-value | Cut-off | Sensitivity | 1-Specificity | |
|---|---|---|---|---|---|---|---|
| Downregulated | miR-885 | 0.9181 | 0.8276–1.000 | < 0.0001 | 0.0357 | 0.8889 | 0.9474 |
| miR-92a | 0.7427 | 0.5925–0.8929 | = 0.0015 | 0.814 | 0.7222 | 0.6842 | |
| miR-338 | 0.7339 | 0.5827–0.8851 | = 0.0024 | 1.7878 | 0.6111 | 0.7895 | |
| Upregulated | miR-21 | 0.9825 | 0.9825–0.9825 | < 0.0001 | 1.6250 | 0.9444 | 0.9474 |
| miR-379 | 0.9211 | 0.8328–1.000 | < 0.0001 | 11.5688 | 1.000 | 0.7895 | |
| W-AV* | miR-379 + miR-21 + miR-885 | 0.9854 | 0.9854–0.9854 | < 0.0001 | 0.1654 | 1.000 | 0.9444 |
| W-AV-HN** | miR-379 + miR-21 + miR-885 | 0.8923 | 0.759–1.000 | < 0.0001 | 0.5528 | 0.9231 | 0.8000 |
*W-AV = weighted average relative quantification of miR-379 + miR-21 + miR-885 in healthy versus MCT samples.
**W-AV-HN = weighted average relative quantification of miR-379 + miR-21 + miR-885 in HN0/1 versus HN2 samples.