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. 2020 Nov 3;10:18918. doi: 10.1038/s41598-020-75877-x

Table 2.

The area under the curve (AUC), sensitivity and specificity values of DE-miRNAs.

miRNA AUC 95% CI P-value Cut-off Sensitivity 1-Specificity
Downregulated miR-885 0.9181 0.8276–1.000  < 0.0001 0.0357 0.8889 0.9474
miR-92a 0.7427 0.5925–0.8929  = 0.0015 0.814 0.7222 0.6842
miR-338 0.7339 0.5827–0.8851  = 0.0024 1.7878 0.6111 0.7895
Upregulated miR-21 0.9825 0.9825–0.9825  < 0.0001 1.6250 0.9444 0.9474
miR-379 0.9211 0.8328–1.000  < 0.0001 11.5688 1.000 0.7895
W-AV* miR-379 + miR-21 + miR-885 0.9854 0.9854–0.9854  < 0.0001 0.1654 1.000 0.9444
W-AV-HN** miR-379 + miR-21 + miR-885 0.8923 0.759–1.000  < 0.0001 0.5528 0.9231 0.8000

*W-AV = weighted average relative quantification of miR-379 + miR-21 + miR-885 in healthy versus MCT samples.

**W-AV-HN = weighted average relative quantification of miR-379 + miR-21 + miR-885 in HN0/1 versus HN2 samples.