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. 2020 Oct 21;11:501383. doi: 10.3389/fphys.2020.501383

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Copyright © 2020 Vanderstocken, Marrow, Allwood, Stampfli and Simpson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Physiological responses of SBP at baseline, week 1, 4, and 8 of cigarette smoke exposure, and cessation week 4. (A) Hourly averages for cigarette smoke exposure and cessation experiments. Horizontal gray bars represent the mesor at baseline (103.2 mmHg). Average SBP during (B) lights on and (C) lights off. Dunnett’s post hoc test was performed on normally distributed data sets. For non-normally distributed data, Kruskal–Wallis’ test was used with Dunn’s post hoc test. *P < 0.05 compared to baseline was considered statistically significant. All values are mean ± SEM (n = 7 at baseline, n = 4 at week 1, n = 3 at week 4, n = 3 at week 8, n = 2 at week 24, and n = 2 at cessation week 4).