Table 2.

Treatment-emergent adverse events that occurred at least twice in the total safety population of substudy 1

Adverse events (preferred term)	Patient 1	Patient 2	Patient 3	Patient 4
Fatigue	✓	✓	–	✓
Upper respiratory tract infection	–	–	✓	✓
Headache	–	✓	–	✓
Alopecia	–	✓	✓	–