TABLE 4.

LMHFV effects on osteocytes.

References	Cells	Frequency (Hz)	Magnitude (*g)	Time schedule	Main outcome
Thompson et al., 2015	Stem cell derived-osteocytes (SCD-O)	90	0.7	2 × 20 min/day (> 3 h in between) for 3 days	SOST↓ No changes in osteocyte differentiation or mineralization, as well as RANKL or OPG expression
Uzer et al., 2014	MLO-Y4 cells	30,100	0.15 1	30 min/day	Gap junctional intracellular communication (GJIC) ↑ Akt-signaling involved
Sakamoto et al., 2019	MLO-Y4 cells	48.3	0.5	1 min	RANKL mRNA ↑ NF-κB activation ↑