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. 2020 Jul 1;30(12):6135–6151. doi: 10.1093/cercor/bhaa159

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© The Author(s) 2020. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Endogenous NA release does not modulate resting intrinsic cellular properties. (A–C) Timecourse of changes in resting membrane potential (V_m) from baseline showing no effect of endogenous NA release (A) or 600 nM NA (B) but a hyperpolarization caused by 20 μM NA (C). (D) Group data for effects of all conditions on V_m. (E–G) Timecourse of changes in input resistance (R_in) from baseline showing no effect of endogenous NA release (E), 600 nM NA (F) and 20 μM NA (G). Example traces are inset. Scales bars = 5 mV, 200 ms. (H) Group data for effects of all conditions on R_in.