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. 2020 Jul 13;30(12):6238–6253. doi: 10.1093/cercor/bhaa181

Table 2.

Definition and categorization of neurological injuries

Factor Category (n = scans)
None-mild injury Severe injury
IVH (Ahmann et al. 1980; Volpe 1981) Grade 0–2 (n = 159) Grade 3–4 (n = 56 scans)
- Bleeding into the ventricles of the brain.
- Overall occurrence rate of approximately 15%.
- IVH occurs in 40% of premature neonates who weigh less than 1500 g.
VM (Perlman and Rollins 2000; Mehlhorn et al. 2017) Grade 0–1 (n = 208) Grade 2–4 (n = 33)
-Dilatation of the lateral cerebral ventricles, usually defined as greater than 10 mm at the level of the atria.
-Prevalence of 0.3–1.5 per 1000 live births.
WMI (Perlman et al. 1996; Volpe 1997; Imamura et al. 2013) Grade 0–1 (n = 196) Grade 2–3 (n = 57)
-Type of brain damage that affects the brain’s white matter and can lead to a series of disabilities, including cerebral palsy.
-Reported incidence of PVL varies from 3% to 15%.
-Periventricular leukomalacia is seen in 3% to 10% of premature neonates.