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. 2020 Sep 18;5(11):1982–1992. doi: 10.1016/j.ekir.2020.09.006

Table 3.

Test performance of the urinary neutrophil gelatinase-associated lipocalin dipstick in the final cohort

Dipstick categories AKI outcome Confounder restrictions
n Sensitivity Specificity PPV NPV Accuracy Prevalence +LR −LR χ2 P value
UTI status Baseline eGFR
A Low vs. high sAKI vs. no AKI or tAKI Any All 278 0.67 0.75 0.16 0.97 0.75 0.06 2.71 0.44 14.99 <.001
B Low vs. high sAKI vs. no AKI or tAKI −UTI eGFR > 30 190 0.60 0.89 0.24 0.98 0.88 0.05 5.68 0.45 20.27 <.001
C Low or intermediate vs. high sAKI vs. no AKI or tAKI Any All 318 0.63 0.79 0.16 0.97 0.78 0.06 2.95 0.47 17.12 <.001
D Low or intermediate vs. high sAKI vs. no AKI or tAKI −UTI eGFR > 30 212 0.55 0.91 0.24 0.97 0.89 0.05 5.77 0.50 20.39 <.001

AKI, acute kidney injury; eGFR, estimated glomerular filtration rate; +LR, positive likelihood ratio; −LR, negative likelihood ratio; NPV, negative predictive value; PPV, positive predictive value; sAKI, sustained acute kidney injury; tAKI, transient acute kidney injury; UTI, urinary tract infection.